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NBL1

neuroblastoma 1, DAN family BMP antagonist

Synonyms:
D1S1733E, DAN, DAND1, NB, NO3
Species:
UniProtKB ID:
Gene ID:
  • Human(4681) Summary: This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]
  • Mouse(17965) neuroblastoma, suppression of tumorigenicity 1
  • Rat(50594) neuroblastoma 1, DAN family BMP antagonist
  • Zebrafish(404629) neuroblastoma, suppression of tumorigenicity 1
  • cow(535280) neuroblastoma 1, DAN family BMP antagonist
  • Horse(100071893) neuroblastoma, suppression of tumorigenicity 1
  • dog(487403) neuroblastoma, suppression of tumorigenicity 1
  • domestic cat(101090533) neuroblastoma, suppression of tumorigenicity 1
  • chicken(373952) neuroblastoma, suppression of tumorigenicity 1
  • sheep(101108197) neuroblastoma, suppression of tumorigenicity 1
  • domestic guinea pig(100732484) neuroblastoma 1, DAN family BMP antagonist
  • naked mole-rat(101708204) neuroblastoma 1, DAN family BMP antagonist

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ELISA

Product Number
Description
Species
Human DAN ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-NBL1 antibody produced in mouse, clone 2G4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-NBL1 antibody produced in mouse, clone 1G5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-NBL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NBL1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-NBL1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Nbl1,
Species
mouse
MISSION® esiRNA, targeting human NBL1, MINOS1-NBL1,
Species
human