KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Synonyms:
C-Kit, CD117, PBT, SCFR
Species:
Human KIT (3815), Mouse Kit (16590), Rat Kit (64030), chicken KIT (378783), domestic cat KIT (493766), cow KIT (280832), Horse KIT (100009704), dog KIT (403811), Goat KIT (100861386), sheep KIT (780504) ...More
UniProtKB ID:
Gene ID:
- Human(3815) Summary: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(16590) kit oncogene
- Rat(64030) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- chicken(378783) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- domestic cat(493766) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- cow(280832) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- Horse(100009704) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- dog(403811) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- Goat(100861386) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- sheep(780504) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- Domestic Rabbit(100327263) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- domestic guinea pig(100726397) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- naked mole-rat(101726400) v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD117 antibody produced in mouse, clone 104D2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
bovine, human, nonhuman primates
Application
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
Anti-phospho-KIT (pTyr721) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Monoclonal Anti-CD117/cKit antibody produced in mouse, clone 104D2,
Species Reactivity
bovine, human, nonhuman primates
Application
flow cytometry
Anti-phospho-c-Kit (Tyr568/Tyr570) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
ANTI-KIT antibody produced in mouse, clone 3A8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
c-Kit Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant, human Kit, amino acids 544-end, for use in Kinase Assays.,
Species
human
c-Kit (D816H) Protein, active, 10 µg, Active, N-terminal GST tagged, recombinant, human c-Kit, amino acids 544-end containing the mutation D816H, for use in Kinase Assays.,
Species
human
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥22% (SDS-PAGE),
Species
human
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Species
human
cKit active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥32% (SDS-PAGE),
Species
human