Birman Group – Professor Product Portal
Professor Vlad Birman
The main focus of research in the Birman group is on the de novo design of asymmetric catalysts and reagents. As part of this effort, they have developed Amidine-Based Catalysts, or ABCs, and demonstrated their high enantioselectivity in many asymmetric acyl transfer reactions. The versatility, accessibility, and ease of structural modification of ABCs have attracted the interest of a number of other research groups worldwide, which has led to further expansion of their synthetic utility.
Birman Group Website
Recent articles from the Birman Group:
1.
Yang X, Bumbu VD, Liu P, Li X, Jiang H, Uffman EW, Guo L, Zhang W, Jiang X, Houk KN, et al. 2012. Catalytic, Enantioselective N-Acylation of Lactams and Thiolactams Using Amidine-Based Catalysts. J. Am. Chem. Soc.. 134(42):17605-17612. http://dx.doi.org/10.1021/ja306766n
2.
Li X, Jiang H, Uffman EW, Guo L, Zhang Y, Yang X, Birman VB. 2012. Kinetic Resolution of Secondary Alcohols Using Amidine-Based Catalysts. J. Org. Chem.. 77(4):1722-1737. http://dx.doi.org/10.1021/jo202220x
3.
Yang X, Birman VB. 2011. Kinetic Resolution of α-Substituted Alkanoic Acids Promoted by Homobenzotetramisole. Chem. Eur. J.. 17(40):11296-11304. http://dx.doi.org/10.1002/chem.201101028
Products available from the Birman Group:
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DISCIPLINES
- Organic Synthetic Chemistry
- Catalysis