The Alexanian group produces functionalized amides that enable a broad range of practical aliphatic C–H transformations. These reactions proceed in useful chemical yields with the substrate as limiting reagent under visible light or radical initiation. The C–H functionalizations occur with good levels of site selectivity, and a variety of common functionality is tolerated. The versatility of the functional groups introduced via these reactions unlocks a wide array of C–H transformations for organic synthesis.
Alexanian Group Website