跳轉至內容
Merck
HomeMILLIPLEX® Multiplex for Luminex® ImmunoassaysMultiplexing Cancer & Metastasis Signaling Pathways

Multiplexing Cancer & Metastasis Signaling Pathways

Cancer and metastasis signaling pathways are notorious for being complex. Read on to see how multiplexing with highly verified MILLIPLEX® multiplex assays can help simplify cancer research by measuring multiple circulating biomarkers at once.


Cancer and Metastasis Signaling Pathways

Cancer and metastasis signaling involves many different pathways including cell signaling, DNA damage, and inflammation. To investigate them, researchers need to analyze various proteins in these pathways such as the Src family kinase, JAK-STAT proteins, TGFβ, NFκB, mTOR, and more. Figure 1 gives a general overview of these pathways and related proteins.

General overview of cancer and metastasis signaling pathways which can be easily analyzed through multiplexing with MILLIPLEX® multiplex immunoassays.

Figure 1Overview of cancer and metastasis signaling pathways highlighting related protein biomarkers.


Multiplexing Signaling Proteins with MILLIPLEX® Multiplex Assays

Multiplexing signaling proteins allows you to measure multiple circulating biomarkers, phosphorylated, or total proteins in a pathway with a single small sample, using intracellular and circulating multiplex assay panels. MILLIPLEX® multiplex assays give you a head start on your research by enabling you to work faster and smarter than traditional techniques, including ELISAs, Western blotting, and flow cytometry. Research areas covered by these panels include:

Related Multiplex Panels

View MILLIPLEX® multiplex panels that can be used to analyze specific cancer and metastasis signaling pathways below.

Receptor Tyrosine Kinase (RTK) Signaling
Loading

Src Family Kinase Signaling
Loading

Transforming Growth Factor Beta (TGFβ) Signaling
Loading

Janus Kinase-Signal Transducer and Activator of Transcription (JAK-STAT) Signaling
Loading

Mitogen-Activated Protein Kinase (MAPK) and Stress-Activated Protein Kinase (SAPK) Signaling
Loading

Mammalian Target of Rapamycin (mTOR) Signaling
Loading

Protein Translation Signaling
Loading

Nuclear Factor Kappa B (NFκB) Signaling
Loading

Early Apoptosis Signaling
Loading

Bcl-2 Family Signaling
Loading

DNA Damage/Genotoxicity Signaling
Loading

For Research Use Only. Not For Use In Diagnostic Procedures.

登入以繼續

若要繼續閱讀,請登入或建立帳戶。

還沒有帳戶?