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  • A highly selective, organocatalytic route to chiral 1,2-oxazines from ketones.

A highly selective, organocatalytic route to chiral 1,2-oxazines from ketones.

Chemical communications (Cambridge, England) (2006-10-10)
Sirirat Kumarn, David M Shaw, Steven V Ley
摘要

A sequential, organocatalysed asymmetric reaction to access chiral 1,2-oxazines from achiral ketone starting materials is reported, which proceeds in moderate to good yields and excellent enantioselectivity.

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Sigma-Aldrich
(S)-5-(吡咯烷-2-基)-1H-四唑, 96%