- The metabolism of ethosuximide.
The metabolism of ethosuximide.
European journal of drug metabolism and pharmacokinetics (1993-10-01)
J S Millership, J Mifsud, P S Collier
PMID8020533
摘要
The metabolism of the antiepileptic drug ethosuximide (3-ethyl-3-methylpyrollidine-2,5-dione) (I) in animals and humans is reviewed. Chiral aspects of the metabolism of ethosuximide are discussed. Clarification of the precise nature of the hydroxymetabolites of ethosuximide is presented.