Novel aminoethylbiphenyls as 5-HT7 receptor ligands.

Novel aminoethylbiphenyls as 5-HT7 receptor ligands.

Bioorganic & medicinal chemistry letters (2007-04-10)

Magalie Paillet-Loilier, Frédéric Fabis, Alban Lepailleur, Ronan Bureau, Sabrina Butt-Gueulle, François Dauphin, Aurélien Lesnard, Catherine Delarue, Hubert Vaudry, Sylvain Rault

PMID17419056

摘要

The synthesis of a series of aminoethylbiphenyls as novel 5-HT(7) receptor ligands is described. The novel derivatives exhibit high affinity for the 5-HT(7) receptor with selectivity toward 5-HT(1A) receptor.

材料

產品編號

品牌

產品描述

260088

Sigma-Aldrich

3-溴氰苄, 98%

534080

Sigma-Aldrich

3-溴苯乙胺, 97%