Potassium iodide catalyzed simultaneous C3-formylation and N-aminomethylation of indoles with 4-substituted-N,N-dimethylanilines.

Potassium iodide catalyzed simultaneous C3-formylation and N-aminomethylation of indoles with 4-substituted-N,N-dimethylanilines.

Organic & biomolecular chemistry (2012-11-13)

Lan-Tao Li, Hong-Ying Li, Li-Juan Xing, Li-Juan Wen, Peng Wang, Bin Wang

摘要

A one-pot dual functionalization of indoles has been developed. The simultaneous C3-formylation and N-aminomethylation of indoles can be achieved using readily available potassium iodide as a catalyst and tert-butyl peroxybenzoate as a co-oxidant.

材料

產品編號

品牌

產品描述

221945

Sigma-Aldrich

碘化钾, ACS reagent, ≥99.0%

207969

Sigma-Aldrich

碘化钾, ReagentPlus^®, 99%

30315

Sigma-Aldrich

碘化钾, puriss. p.a., reag. ISO, reag. Ph. Eur., ≥99.0%

651818

Sigma-Aldrich

金蚀刻剂，标准

204102

Sigma-Aldrich

碘化钾, ≥99.99% trace metals basis

03124

Sigma-Aldrich

碘化钾, puriss., meets analytical specification of Ph. Eur. BP, USP, 99.0-100.5% (calc. to the dried substance)

60399

Sigma-Aldrich

碘化钾, BioUltra, ≥99.5% (AT)

236233

Sigma-Aldrich

N-甲基苯胺, ≥99%

M29304

Sigma-Aldrich

N-甲基苯胺, 98%

P8166

Sigma-Aldrich

碘化钾, suitable for plant cell culture

429422

Sigma-Aldrich

碘化钾, AnhydroBeads^™, −10 mesh, 99.998% trace metals basis

60422

Sigma-Aldrich

碘化钾, tested according to Ph. Eur.

P2963

Sigma-Aldrich

碘化钾, BioXtra, ≥99.0%

209872

Sigma-Aldrich

4-叔丁基-N,N-二甲基苯胺, 98%

49636

Supelco

N-甲基苯胺, analytical standard

65760

Sigma-Aldrich

N-甲基苯胺, purum, ≥98.0% (GC)