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Merck
  • Phytosterols as anticancer dietary components: evidence and mechanism of action.

Phytosterols as anticancer dietary components: evidence and mechanism of action.

The Journal of nutrition (2000-08-26)
A B Awad, C S Fink
摘要

Phytosterols (PS) or plant sterols are structurally similar to cholesterol. The most common PS are beta-sitosterol, campesterol and stigmasterol. Epidemiologic and experimental studies suggest that dietary PS may offer protection from the most common cancers in Western societies, such as colon, breast and prostate cancer. This review summarizes the findings of these studies and the possible mechanisms by which PS offer this protection. These include the effect of PS on membrane structure and function of tumor and host tissue, signal transduction pathways that regulate tumor growth and apoptosis, immune function of the host and cholesterol metabolism by the host. In addition, suggestions for future studies to fill the gaps in our knowledge have been given.

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品牌
產品描述

Sigma-Aldrich
豆甾醇, ~95%
Avanti
sitosterol, Avanti Polar Lipids