Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.

Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A.

Journal of medicinal chemistry (2008-04-09)

Gavin Carr, Marco K W Chung, A Grant Mauk, Raymond J Andersen

摘要

Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.

材料

產品編號

品牌

產品描述

219878

Sigma-Aldrich

对羟基吲哚, 99%

860646

Sigma-Aldrich

1-甲基-DL-色氨酸, 97%