Epidermal growth factor receptor as a biomarker for cervical cancer.

Epidermal growth factor receptor as a biomarker for cervical cancer.

Annals of oncology : official journal of the European Society for Medical Oncology (2011-02-18)

T Soonthornthum, H Arias-Pulido, N Joste, L Lomo, C Muller, T Rutledge, C Verschraegen

摘要

This review focuses on the different modes of expression of the epidermal growth factor receptor (EGFR). All methods used to assess EGFR expression are critically analyzed and insights into the use of inhibitors of EGFR for treatment of cervical cancer are discussed. Currently, expression of EGFR as a biomarker for prognosis or for treatment of cervical cancer is not defined for clinical use.