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Merck

Stereoselective construction of nitrile-substituted cyclopropanes.

Chemical communications (Cambridge, England) (2008-03-01)
Justin R Denton, Kevin Cheng, Huw M L Davies
摘要

Nitrile-substituted cyclopropanes are readily synthesized in a stereocontrolled fashion from the intermolecular cyclopropanation between 2-diazo-2-phenylacetonitrile and electron-rich olefins, catalyzed by the chiral dirhodium complex, Rh(2)(S-PTAD)(4).