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Merck
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Key Documents

T5067

Sigma-Aldrich

Anti-TRPC3 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

同義詞:

Anti-Transient receptor potential cation channel, subfamily C, member 3

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

物種活性

rat

濃度

≥0.6 mg/mL (after reconstitution)

技術

western blot: suitable

UniProt登錄號

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

mouse ... Trpc3(22065)
rat ... Trpc3(60395)

一般說明

Transient receptor potential-canonical 3 (TRPC3) is a member of TRP superfamily. It is mainly expressed in brain. The TRPC3 gene is mapped to human chromosome 4.

免疫原

peptide corresponding to amino acid residues 822-835 of mouse TRPC3.

生化/生理作用

TRPC3 (transient receptor potential-canonical 3) participates in motility and capacitation of sperm. It is responsible for the proliferation of ovarian cancer cell in vitro and in vivo. TRPC3 plays a key role in a wide spectrum of Ca2+ signaling mechanisms. Elevated expression of TRPC3 has been observed in spontaneously hypertensive rats (SHR).

外觀

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

TRPC3: A Multifunctional Signaling Molecule
Lichtenegger M and Groschner K
Handbook of Experimental Pharmacology, 67-84 (2014)
Genotype of an individual single nucleotide polymorphism regulates DNA methylation at the TRPC3 alternative promoter.
Martin-Trujillo A
Epigenetics, 6, 1236-1241 (2011)
Activation of a TRPC3-Dependent Cation Current through the Neurotrophin BDNF
Li HS
Neuron, 24, 261-273 (1999)
Increased Transient Receptor Potential Channel TRPC3 Expression in Spontaneously Hypertensive Rats
Liu D
American Journal of Hypertension, 18, 1503-1507 (2005)
Follicle-stimulating hormone enhances the proliferation of ovarian cancer cells by activating transient receptor potential channel C3
Tao X
Endocrine-Related Cancer, 20, 415-429 (2013)

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