SML3907

CNS-11g

≥98% (HPLC)

• 同義詞: 2-(4-benzyl-1-oxo-2(1H)-phthalazinyl)-N-(2,6-dimethylphenyl)acetamide, N-(2,6-Dimethylphenyl)-1-oxo-4-(phenylmethyl)-2(1H)-phthalazineacetamide
• 經驗公式（希爾表示法）: C₂₅H₂₃N₃O₂
• CAS號碼: 1309252-87-6
• 分子量：: 397.47
• MDL號碼: MFCD19028082
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 2 mg/mL, clear (Warmed)
• 儲存溫度: 2-8°C

描述

生化／生理作用

Brain tissue penetrant alpha-synuclein ligand that potently disaggregate alpha-synuclein fibrils in vitro and in vivo models.
CNS-11g is brain tissue penetrant alpha-synuclein ligand that potently disaggregate alpha-synuclein fibrils in vitro and in vivo models. CNS-11g inhibits intracellular seeding of a-synuclein fibrils in biosensor cells-HEK293T cells and mitigate a-synuclein cytotoxicity in Neuro-2a (N2a) neuronal cells. C-11g reduces number of a-synuclein aggregates in C. elegans model.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable