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Key Documents

SAB5702356

Sigma-Aldrich

Anti-NADPH oxidase 4 (NOX4) Antibody, clone 6Q3U8, Rabbit Monoclonal

同義詞:

KOX, KOX-1, RENOX

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About This Item

分類程式碼代碼:
12352203

生物源

rabbit

品質等級

材料

colorless

無性繁殖

6Q3U8, monoclonal

形狀

liquid

分子量

67 kDa

物種活性

human, mouse, rat

濃度

1.37 mg/mL

技術

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

LHNKFWQENRPDYVNIQLYLSQTDGIQKIIGEKYHALNSRLFIGRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKTLHKLSNQNNSYGTRFEYNKESFS

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... NOX4(50507)

一般說明

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 479-578 of human NADPH oxidase 4 (NOX4) (Q9NPH5).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IHC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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