SAB5700452

Anti-Phospho-ACLY-S455 antibody produced in rabbit

• 同義詞: ACL, ACLY, ATPCL, CLATP
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 119; 120; 91
• 物種活性: rat, mouse, human
• 濃度: 1.15 mg/ml
• 技術: immunohistochemistry: 1:50-1:100; immunoprecipitation (IP): 1:50-1:100; western blot: 1:500-1:2000
• UniProt登錄號: P53396
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pSer455)
• 基因資訊: human ... ACLY(47)

描述

一般說明

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

免疫原

A synthetic phosphorylated peptide around S455 of human ACLY (NP_001087.2).

外觀

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

儲存和穩定性

Store at -20℃. Avoid freeze / thaw cycles.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable