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Key Documents

SAB4503912

Sigma-Aldrich

Anti-phospho-ETS1 (pThr38) antibody produced in rabbit

affinity isolated antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 50 kDa

物種活性

rat, human, mouse

濃度

~1 mg/mL

技術

ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

phosphorylation (pThr38)

基因資訊

human ... ETS1(2113)

一般說明

ETS1 (E26 transformation specific sequence 1) is a proto‐oncogene. It is a member of the family of ETS transcriptional factors. ETS1 is usually expressed in lymphoid cells. This gene is mapped to human chromosome 11q24.

免疫原

The antiserum was produced against synthesized peptide derived from human ETS1 around the phosphorylation site of Thr38.

Immunogen Range: 11-60

生化/生理作用

ETS1 (E26 transformation specific sequence 1) participates in Pol ι‐mediated progression of ESCC (esophageal squamous cell carcinoma). This gene controls cancer cell invasion, metastasis and EMT (epithelial to mesenchymal transition). ETS1 also plays important roles in the lymphocyte development, function, apoptosis and inflammation.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

Submicroscopic deletions of 11q24-25 in individuals without Jacobsen syndrome: re-examination of the critical region by high-resolution array-CGH
Tyson C, et al.
Molecular Cytogenetics (2008)
Association of E26 Transformation Specific Sequence 1 Variants with Rheumatoid Arthritis in Chinese Han Population
Chen L, et al.
PLoS ONE, 10(8) (2015)
Phosphorylation of ETS-1 is a critical event in DNA polymerase iota-induced invasion and metastasis of esophageal squamous cell carcinoma
He C, et al.
Cancer Science, 108(12), 2503-2510 (2017)

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