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I5154

Sigma-Aldrich

IgG1,Kappa 来源于人类骨髓瘤血浆

purified immunoglobulin, >95% (SDS-PAGE)

同義詞:

人 IgG1--κ

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

human

品質等級

共軛

unconjugated

抗體表格

purified immunoglobulin

化驗

>95% (SDS-PAGE)

應用

research pathology

運輸包裝

dry ice

儲存溫度

−20°C

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一般說明

IgG抗体亚型是免疫系统中含量最高的血清免疫球蛋白。它由B细胞分泌,存在于血液和细胞外液中,可防止细菌、真菌和病毒引起的感染。母亲的IgG通过胎盘传递给胎儿,对于新生儿抗感染至关重要。IgG1是最丰富的IgG亚型
人骨髓瘤IgG1,κ从人血浆中通过分离,离子交换和亲和层析步骤纯化。

應用

纯化IgG1, κ可用作免疫球蛋白校对物,参考抗原,抑制剂或覆盖蛋白,用于各种免疫分析包括ELISA,点印迹免疫结合,Western免疫印迹,免疫扩散,免疫电泳,血凝反应和细胞结合分析。人骨髓瘤IgG1κ 被注入小鼠体内,用来评估T细胞和B细胞应答,还用于CHO细胞流式细胞仪。

外觀

溶解在0.02M Tris缓冲液溶液,pH8.0。

分析報告

特性可以通过免疫电泳和非直接ELISA确定。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Bas Cornelis Jansen et al.
PloS one, 13(7), e0200280-e0200280 (2018-07-07)
High-performance liquid chromatography (HPLC) is widely used for absolute quantitation. The advent of new columns and HPLC technology has enabled higher sample throughput, and hence, larger scale studies that perform quantitation on different sample types (e.g. healthy controls vs. patients
Johnny W Peterson et al.
Infection and immunity, 74(2), 1016-1024 (2006-01-24)
Prevention of inhalation anthrax requires early and extended antibiotic therapy, and therefore, alternative treatment strategies are needed. We investigated whether a human monoclonal antibody (AVP-21D9) to protective antigen (PA) would protect mice, guinea pigs, and rabbits against anthrax. Control animals
Yann Gallais et al.
Immunology and cell biology, 95(3), 306-315 (2016-10-08)
Patients treated with therapeutic biological products (BP) frequently develop anti-drug antibodies (ADA) with potential neutralizing capacities leading to loss of clinical response or serious side effects. BP aggregates have been suggested to promote immunogenicity, thus enhancing ADA production. Dendritic cells
Bor-Ching Sheu et al.
Biosensors & bioelectronics, 26(2), 822-827 (2010-07-09)
Emerging evidence indicates that the conformation of C-reactive protein (CRP) plays important roles in human inflammation and cardiovascular disease (CVD). The different conformations in the structure of CRP under different pH conditions remain an important issue to be investigated for
Taehong Kwon et al.
Analytical chemistry, 92(7), 5267-5275 (2020-03-14)
We demonstrate a new micro/nanofluidic system for continuous and automatic monitoring of protein product size and quantity directly from the culture supernatant during a high-cell-concentration CHO cell perfusion culture. A microfluidic device enables clog-free cell retention for a bench-scale (350

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