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Merck
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Key Documents

EHU085031

Sigma-Aldrich

MISSION® esiRNA

targeting human NADK

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About This Item

分類程式碼代碼:
41105324
NACRES:
NA.51

描述

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產品線

MISSION®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

TGACTCGACCTGTCCTTCAATGTTGATAATAAATGTCTCAGCCAAAAACCTTCCTTGAGCTGCCATGCTTTTCCCCTTGACCTGCACCTCTTCCCCTAAAACTTCTGCAGGGAAGCCCCTGGCGGAGGCGCCATTGAAAGCATGGTCTTGCCAGTGGCTGGCAAGGCGGTTTTGTTCTGCTCAGTTTCTGGAGAGGGTTGGATGCGTCCCCTGCCATCCAGCCCTCCCCGCTTGAGGCCAGCACTGAGTCTGGGACACTCAGCGGGAAGGGGGCTGGCATCGCCAGCGACCCACACATTCCTCACGTAGCTTCTGCTCCCAGGAAGGTAGTTTAAATCCTGTATATACTTTTTAGAGACTCTTTTAAACTTTCTGAAGTGCTGATGTACATACTTTCTCGTACACACTTTTGTGAAGATTTCAAGGGGAAGGGA

Ensembl | 人類登錄號

ENSG00000008130

NCBI登錄號

NM_023018

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

human ... NADK(65220) , NADK(65220)

一般說明

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Gerta Hoxhaj et al.
Science (New York, N.Y.), 363(6431), 1088-1092 (2019-03-09)
Nicotinamide adenine dinucleotide phosphate (NADP+) is essential for producing NADPH, the primary cofactor for reductive metabolism. We find that growth factor signaling through the phosphoinositide 3-kinase (PI3K)-Akt pathway induces acute synthesis of NADP+ and NADPH. Akt phosphorylates NAD kinase (NADK)

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