SCC225

YUMM 1.3 Mouse Melanoma Cell Line

Mouse

• 同義詞: Yale University Mouse Melanoma 1.3 cell line, Yale University Mouse Melanoma cell line
• 分類程式碼代碼: 41106514
• NACRES: NA.81

屬性

• product name: YUMM 1.3 Mouse Melanoma Cell Line,
• 生物源: mouse
• 品質等級: 100
• 包裝: vial of ≥1X10⁶ vial
• 製造商／商標名: Millipore
• 技術: cell culture | mammalian: suitable
• 運輸包裝: liquid nitrogen
• 儲存溫度: −196°C

描述

一般說明

YUMM1.3 cells are syngeneic with the immunocompetent C57BL/6 mouse background and retain genetic markers of the Braf/Pten mouse models, characterized by activation of Braf and inactivation of Pten and Cdkn2a.

應用

• Each vial contains >1X10⁶ viable cells.
• YUMM1.3 cells are tested negative for infectious diseases by a Mouse Essential CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are verified to be of mouse origin and negative for inter-species contamination from rat, chinese hamster, Golden Syrian hamster, human and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are negative for mycoplasma contamination.

特點和優勢

​ The YUMM cell models recapitulate genetic drivers found in a significant proportion of human melanomas. YUMM1.3 cells retain genetic markers of the Braf/Pten mouse models, characterized by activation of Braf and inactivation of Pten and Cdkn2a, in which

標靶描述

Immunocompetent genetically-engineered mouse models harboring discrete genetic drivers of melanoma are essential for studying potential immunotherapies but are limited by the need to maintain colonies of multiple genotypes necessary to generate mouse mode

儲存和穩定性

YUMM1.3 cells should be stored in liquid nitrogen until use. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.

其他說明

This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact l

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable