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Key Documents

PC57

Sigma-Aldrich

Anti-MSH2 (Ab-3) Rabbit pAb

liquid, Calbiochem®

同義詞:

Anti-Mismatch Repair Protein 2

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About This Item

分類程式碼代碼:
12352203

生物源

rabbit

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

liquid

不包含

preservative

物種活性

human, mouse

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
avoid repeated freeze/thaw cycles

同型

IgG

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... MSH2(4436)

一般說明

Purified rabbit polyclonal antibody. Recognizes the ~100 kDa MSH2 protein.
Recognizes the ~100 kDa MSH2 protein in HCT116 and SW480 cells and in colon tissue.
This Anti-MSH2 (Ab-3) Rabbit pAb is validated for use in Frozen Sections, Immunoblotting, Immunoprecipitation, Paraffin Sections for the detection of MSH2 (Ab-3).

免疫原

full length, recombinant, human MSH2

應用

Frozen Sections (2 µg/ml)

Immunoblotting (1 µg/ml, chemiluminescence)

Immunoprecipitation (1 µg/sample)

Paraffin Sections (see application references)

包裝

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

其他說明

Bronner, C.E., et al. 1994. Nature368, 258.
Papadopoulos, N., et al. Science263, 1625.
Peltomäki, P.T. 1994. Ann. Medicine26, 215.
Fishel, R., et al. 1993. Cell75, 1027.
Leach, F.S., et al. 1993. Cell75, 1215.
Lindbolm, A., et al. 1993. Nat. Genet.5, 279.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°C)

Not applicable


分析證明 (COA)

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J Barwell et al.
Journal of medical genetics, 44(8), 516-520 (2007-05-08)
Reports of differential mutagen sensitivity conferred by a defect in the mismatch repair (MMR) pathway are inconsistent in their conclusions. Previous studies have investigated cells established from immortalised human colorectal tumour lines or cells from animal models. We examined primary
Jennifer A McKinney et al.
Nature communications, 11(1), 236-236 (2020-01-15)
Alternative DNA structure-forming sequences can stimulate mutagenesis and are enriched at mutation hotspots in human cancer genomes, implicating them in disease etiology. However, the mechanisms involved are not well characterized. Here, we discover that Z-DNA is mutagenic in yeast as

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