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Key Documents

EI6

Sigma-Aldrich

Chymostatin

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About This Item

分類程式碼代碼:
12352200
eCl@ss:
32160405
NACRES:
NA.77

製造商/商標名

Chemicon®

品質等級

運輸包裝

dry ice

一般說明

Chymostatin. M.W. 604.92

Mixture of types A, B and C. Inhibits Chymotrypsin-like serine proteases including alpha, beta, gamma and delta chymotrtrypsins.

Sequence:

[(S)-1-Carboxy-2-Phenylethyl]-Carbamoyl-a-[2-Iminohexahydro-4(S)-Pyrimidyl]-(S)-Glycyl-X-Phenylalaninal

X: L-Leu (type A), L-Ile (type B), L-Val (type C)

Working concentrations 10-100μM.

Stable for several hours. Soluble in DMSO and glacial acetic acid. Solutions are stable for a month at -20ºC.

5mg/825 microliters in DMSO = 10mM solution.

Dilute 1:100 for 100μM working solution.

生化/生理作用

Inhibitor Type: Protease Inhibitors

外觀

Lyophilized. Dissolve in dimethylsulfoxide (DMSO). After powder is thoroughly dissolved, dilute the DMSO solution with 0.9% NaCl. The concentration of DMSO should be maintained at 10% or higher. Otherwise chymostatin may precipitate from the solution.



Example: Reconstitute 1 mg of chymostatin with 1.65 mL of DMSO. Then add 14.85 mL of 0.9% NaCl. This furnishes a 10-4 M solution. No preservatives added.

儲存和穩定性

Maintain lyophilized material at -20ºC for up to one year. Store reconstituted product in aliquots at -20ºC for up to 3-4 weeks. Do not thaw and refreeze.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Chymostatin, a new chymotrypsin inhibitor produced by actinomycetes.
H Umezawa et al.
The Journal of antibiotics, 23(8), 425-427 (1970-08-01)

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