ABN998

Anti-phospho PSD95 Antibody (Thr19)

from rabbit, purified by affinity chromatography

• 同義詞: Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 90, SAP-90, SAP90
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 物種活性（以同源性預測）: mouse (based on 100% sequence homology), rat (based on 100% sequence homology), bovine (based on 100% sequence homology)
• 技術: immunohistochemistry: suitable (paraffin); inhibition assay: suitable (peptide); western blot: suitable
• NCBI登錄號: NP_001122299
• UniProt登錄號: P78352
• 運輸包裝: wet ice
• 目標翻譯後修改: phosphorylation (pThr19 )
• 基因資訊: human ... DLG4(1742)

描述

一般說明

PSD95 (postsynaptic density95) represent a class of anchoring proteins which serve to localize various neuronal ion channels to post-synaptic densities. PSD95 and related proteins contain PDZ domains, which interact with NMDA receptors and voltage-gated K+ channels via a ET/SXV motif in the cytoplasmic carboxyl terminus of the receptor channels.

免疫原

Epitope: Near N-Terminus

KLH-conjugated linear peptide corresponding to human phospho PSD95 (Thr19) near the N-Terminus.

應用

Anti-phospho PSD95 Antibody (Thr19) is an antibody against phospho PSD95 (Thr19) for use in Western Blotting, Peptide Inhibition Assay, Immunohistochemistry (Paraffin).

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected phospho PSD95 (Thr19) in human cerebellum, human cerebral cortex, and human thalamus tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blotting in human fetal brain tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected phospho PSD95 (Thr19) in 10 µg of human fetal brain tissue lysate.

標靶描述

~80 kDa observed. The calculated molecular weight is 80 kDa, however phospho PSD95 (Thr19) has been shown as a ~80-95 kDa band in some western blots (Nelson, C.D., et al. (2013). J. of Neuroscience. 33(29):12122-12135).

外觀

Affinity

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to lot specific datasheet.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable