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Key Documents

AB1094

Sigma-Aldrich

Anti-Myosin X Antibody

serum, from rabbit

同義詞:

Unconventionnal myosin-X, Unconventional myosin-10

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse, rat, human

技術

western blot: suitable

GenBank登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... MYO10(4651)

一般說明

Myosins are a superfamily of molecular motor proteins found in eukaryotic cells. Motor proteins are involved in muscular contraction, cytokinesis, short-range membrane/vesicle transport and a host of other cellular processes. The myosins are responsible for actin-based motility by using the energy of ATP hydrolysis to generate force and movement along actin filaments. There are many isoforms of myosin of which some have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. Myosin X belongs to a group of myosin isoforms known as unconventional myosins that participate in cellular processes ranging from membrane trafficking to signaling and cell motility. Myosin X is concentrated at the tips of filopodia and Myosin X rich regions travel forward and backward along filopods, (Berg, 2002). It also appears that Myosin X functions in actual filopodia formation, (Bohil, 2006).

特異性

Cat. No. AB1094 recognizes human Myosin X.
Predicted to cross react with mouse and rat based on 100% sequence homology. Reactivity with other species has not been tested.

免疫原

Epitope: a.a. 936-953
KLH-conjugated synthetic peptide to amino acids 936-953 of human Myosin X.

應用

Detect Myosin X using this Anti-Myosin X Antibody validated for use in WB.

品質

Evaluated on a representative lot by Western blot on human head/neck lysate using Anti-Myosin X.

標靶描述

~ 108 kDa

儲存和穩定性

Maintain at -20°C for up to 1 year from date of receipt.
Upon arrival, aliquot into usable quantities to avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析報告

Control
Human head/neck lysate.

法律資訊

GenBank is a registered trademark of United States Department of Health and Human Services

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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