8.52059

Fmoc-Hse(Trt)-OH

Novabiochem^®

• 同義詞: Fmoc-Hse(Trt)-OH, N-α-Fmoc-O-trityl-L-homoserine
• 經驗公式（希爾表示法）: C₃₈H₃₃NO₅
• CAS號碼: 111061-55-3
• 分子量：: 583.67
• MDL號碼: MFCD00270544
• 分類程式碼代碼: 12352209
• NACRES: NA.22

屬性

• 品質等級: 200
• 產品線: Novabiochem^®
• 化驗: ≥80.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• 形狀: powder
• 反應適用性: reaction type: Fmoc solid-phase peptide synthesis
• 製造商／商標名: Novabiochem^®
• 應用: peptide synthesis
• 官能基: hydroxyl
• 儲存溫度: 15-25°C
• InChI: 1S/C38H33NO5/c40-36(41)35(39-37(42)43-26-34-32-22-12-10-20-30(32)31-21-11-13-23-33(31)34)24-25-44-38(27-14-4-1-5-15-27,28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-23,34-35H,24-26H2,(H,39,42)(H,40,41)/t35-/m0/s1
• InChI 密鑰: QUTREFXHXPNEJN-DHUJRADRSA-N

描述

一般說明

Building block which enables side-chain modification of homoserine serines by Fmoc SPPS. The Trt group can be removed with 1% TFA in DCM containing 5% TIS, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This derivative has been employed to prepare oligonucleotide conjugates ^[1].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS


Literature references

^[1] D. A. Stetsenko & M. J. Gait (2001) Bioconjugate Chem. , 12, 576.

聯結

Replaces: 04-12-1126

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 80.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable