5.43899

1-甲基-2-吡咯烷酮

for liquid chromatography LiChrosolv^®

• 同義詞: 1-甲基-2-吡咯烷酮
• 經驗公式（希爾表示法）: C₅H₉NO
• CAS號碼: 872-50-4
• 分子量：: 99.13
• MDL號碼: MFCD00003193
• 分類程式碼代碼: 41116105
• 酶委員會索引編號: 212-828-1

屬性

• 蒸汽壓力: 0.32 hPa ( 20 °C)
• 品質等級: 100
• 產品線: LiChrosolv^®
• 等級: isocratic
• 化驗: ≥99.5% (GC)
• 形狀: liquid
• 自燃溫度: 245 °C
• expl. lim.: 1.3-9.5 % (v/v)
• 技術: HPLC: suitable
• 雜質: ≤0.05% Water
• 透射率: 300 nm, ≥50%; 325 nm, ≥90%; 350 nm, ≥97%; 400 nm, ≥99%
• pH值: 8.5-10.0 (20 °C, 100 g/L in H₂O)
• bp: 202 °C/1013 hPa
• mp: -24 °C
• 轉變溫度: flash point 91 °C
• 溶解度: 1000 g/L
• 密度: 1.03 g/cm³ at 20 °C
• 儲存溫度: 2-30°C
• InChI: 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
• InChI 密鑰: SECXISVLQFMRJM-UHFFFAOYSA-N

描述

應用

• Novel transdermal bioadhesive surfactant-based system for release and solubility improvement of antimalarial drugs artemether-lumefantrine: This study utilizes 1-Methyl-2-pyrrolidone (NMP) as a high-purity solvent in the formulation of a transdermal bioadhesive system, enhancing the solubility and delivery of antimalarial drugs. The application highlights NMP′s role in pharmaceutical formulations, particularly in improving drug efficacy and patient compliance (Volpe-Zanutto et al., 2021).

分析報告

纯度 (GC)： ≥ 99.5 %
水： ≤ 0.05 %
透射率（300 nm处）： ≥ 50 %
透射率（325nm处）： ≥ 90 %
透射率（350nm处）： ≥ 97 %
透射率（400nm处）： ≥ 99 %

其他說明

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

法律資訊

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS07,GHS08
• 訊號詞: Danger
• 危險聲明: H315 - H319 - H335 - H360D
• 防範說明: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• 危險分類: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 195.8 °F - Pensky-Martens closed cup
• 閃點（°C）: 91 °C - Pensky-Martens closed cup