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444105

Sigma-Aldrich

Anti-Mannose 6-Phosphate Receptor Mouse mAb (2G11)

liquid, clone 2G11, Calbiochem®

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

2G11, monoclonal

形狀

liquid

包含

≤0.1% sodium azide as preservative

物種活性

bovine, monkey, human

應無反應活性

hamster

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
avoid repeated freeze/thaw cycles

同型

IgG2a

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... M6PR(4074)

一般說明

Purified mouse monoclonal antibody. Recognizes the mannose 6-phosphate receptor protein.
Recognizes the ~300 kDa mannose 6-phosphate receptor protein.
This Anti-Mannose 6-Phosphate Receptor Mouse mAb (2G11) is validated for use in Immunoblotting, IF, IHC, IP for the detection of Mannose 6-Phosphate Receptor.

免疫原

Bovine
Epitope: within the extracelluar domain
native bovine cation independent (CI)-mannose 6-phosphate receptor

應用

Immunoblotting (1 µg/ml, non-reducing, see comments)

Immunofluorescence (see comments)

Immunohistochemistry (2-5 µg/ml)

Immunoprecipitation (see comments)

包裝

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

外觀

In PBS.

重構

Following initial thaw, aliquot and freeze (-20°C).

其他說明

Dintzis, S., et al. 1994. J. Biol. Chem.269, 12159.
Dintzis, S., and Pfeffer, S. 1990. EMBO J.9, 77.
Does not detect MPR in hamster (CHO) cells. Not suitable for immunoblotting using reducing conditions. This antibody has also been reported to work for immunoprecipitation and immunofluorescence. Variables associated with assay conditions will dictate the proper working dilution.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Jennifer Hirst et al.
Human molecular genetics, 24(17), 4984-4996 (2015-06-19)
Adaptor proteins (AP 1-5) are heterotetrameric complexes that facilitate specialized cargo sorting in vesicular-mediated trafficking. Mutations in AP5Z1, encoding a subunit of the AP-5 complex, have been reported to cause hereditary spastic paraplegia (HSP), although their impact at the cellular

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