171372

Amphiregulin, Human, Recombinant

Amphiregulin, Human, Recombinant, consisting of amino acids 101-198 and is expressed in E. coli. Stimulates the proliferation of various human and mouse keratinocytes.

• 同義詞: Schwannoma-derived growth factor (SDGF)
• 分類程式碼代碼: 12352203
• NACRES: NA.77

屬性

• 重組細胞: expressed in E. coli
• 品質等級: 100
• 化驗: ≥97% (SDS-PAGE)
• 形狀: liquid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 雜質: <1.0 EU/μg protein Endotoxin
• 運輸包裝: ambient
• 儲存溫度: −20°C

描述

一般說明

Recombinant, human amphiregulin (AR) consisting of amino acids 101-198 and expressed in E. coli. Human amphiregulin is able to stimulate the proliferation of various human and mouse keratinocytes, mammary epithelial cells, and some fibroblasts. Shown to be an autocrine growth factor, amphiregulin is also a growth inhibitor for various tumor cells and can bind to the EGF receptor.

生化／生理作用

ED₅₀ = 5-15 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.

警告

Toxicity: Standard Handling (A)

外觀

Lyophilized from 0.2 µm sterile-filtered PBS, BSA.

重構

Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.

Reconstitute to 100 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3