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Key Documents

09-817

Sigma-Aldrich

抗-JMJD1抗体

from rabbit, purified by affinity chromatography

同義詞:

JMJD, jumonji domain containing 1C, TR-interacting protein 8, thyroid receptor interacting protein 8, probable JmjC domain-containing histone demethylation protein 2C, thyroid hormone receptor interactor 8, Thyroid receptor-interacting protein 8, Jumonji

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human

物種活性(以同源性預測)

chimpanzee (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology), orangutan (based on 100% sequence homology), rabbit (based on 100% sequence homology)

技術

immunocytochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... JMJD1C(221037)

一般說明

JMJD1C(含jumonji域的蛋白1C)也称TRIP8,该组蛋白脱甲基酶的突变与某些形式的自闭症有关。JMJD1C也被认为可以重新激活胚胎干细胞、胰岛和胃癌中的基因。JMJD1C也被认为是基因表达调节剂。最近显示带有WHISTLE的JMJD1C在小鼠睾丸发育中也起作用。JMJD1C已被确定为核受体共激活因子,并且是自闭症的候选基因。

免疫原

对应于人JMJD1C的KLH偶联线性肽。

應用

使用经WB、ICC验证的抗-JMJD1C抗体(兔多克隆抗体)检测JMJD1C,也称为含1C或tr相互作用蛋白8的jumonji结构域。
免疫细胞化学分析: 来自代表性批次的1:500稀释液在HeLa细胞中检测到JMJD1C。
研究子类别
组蛋白修饰蛋白
研究类别
表观遗传学&核功能

品質

通过蛋白质印迹对HeLa核提取物进行了评估。

蛋白质印迹分析:1 µg/mL的该抗体在10 µg HeLa核提取物中检测到JMJD1C。

標靶描述

观测值〜284 kDa

外觀

亲和纯化
纯化的兔多克隆抗体,溶于含有0.1 M Tris-甘氨酸(pH 7.4)、150 mM NaCl和0.05%叠氮化钠的缓冲液中。

儲存和穩定性

自收到之日起,在2-8°C条件下可稳定保存1年。

分析報告

对照
HeLa核提取物

其他說明

浓度:请参考批次特异性浓缩物的检验报告。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

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