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Merck
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Key Documents

09-278

Sigma-Aldrich

Anti-20S proteasome subunit β5 Antibody

serum, Upstate®

同義詞:

LMP17, MB1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

human

製造商/商標名

Upstate®

技術

immunohistochemistry: suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

基因資訊

human ... PSMB5(5693)

特異性

Recognizes proteasome subunit β5

免疫原

Peptide corresponding to residues 194-207 of human proteasome subunit β5 conjugated to KLH.

應用

Research Category
Protein Trafficking
Research Sub Category
Ubiquitin & Ubiquitin Metabolism
This Anti-20S proteasome subunit β5 Antibody is validated for use in IH, WB for the detection of 20S proteasome subunit β5.

標靶描述

22 kDa

外觀

antiserum
100 µL of purified antiserum preparation in PBS containing 0.09% sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.

儲存和穩定性

Stable for 1 year at -20°C from date of shipment for up to 12 months.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Cyriel S Olie et al.
iScience, 12, 318-332 (2019-02-11)
Reduced poly(A)-binding protein nuclear 1 (PABPN1) levels cause aging-associated muscle wasting. PABPN1 is a multifunctional regulator of mRNA processing. To elucidate the molecular mechanisms causing PABPN1-mediated muscle wasting, we compared the transcriptome with the proteome in mouse muscles expressing short
Muhammad Riaz et al.
PLoS genetics, 12(5), e1006031-e1006031 (2016-05-07)
Poly(A) Binding Protein Nuclear 1 (PABPN1) is a multifunctional regulator of mRNA processing, and its expression levels specifically decline in aging muscles. An expansion mutation in PABPN1 is the genetic cause of oculopharyngeal muscle dystrophy (OPMD), a late onset and
K Tanaka et al.
Molecular biology reports, 24(1-2), 3-11 (1997-03-01)
The 26S proteasome is an eukaryotic ATP-dependent, dumbbell-shaped protease complex with a molecular mass of approximately 2000 kDa. It consists of a central 20S proteasome, functioning as a catalytic machine, and two large V-shaped terminal modules, having possible regulatory roles

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