N-073

硝甲西泮标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 經驗公式（希爾表示法）: C₁₆H₁₃N₃O₃
• CAS號碼: 2011-67-8
• 分子量：: 295.29
• MDL號碼: MFCD00242916
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329818453
• NACRES: NA.24

屬性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• 濃度: 1.0 mg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: clinical testing
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: CN1C(=O)CN=C(c2ccccc2)c3cc(ccc13)[N+]([O-])=O
• InChI: 1S/C16H13N3O3/c1-18-14-8-7-12(19(21)22)9-13(14)16(17-10-15(18)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3
• InChI 密鑰: GWUSZQUVEVMBPI-UHFFFAOYSA-N

描述

一般說明

尼美西泮以苯二氮卓类药物Erimin的形式销售，用于治疗难以入睡或维持睡眠的患者的压力或短期严重失眠。据报道，东南亚国家（包括泰国、马来西亚、新加坡和香港）向阿拉巴马州和北卡罗来纳州等州报告了滥用案例。尽管在美国没有用于治疗，但该药物以减轻使用甲基苯丙胺或其他兴奋剂后的低迷而闻名。

應用

• Advanced Analytical Techniques for Benzodiazepines: Nimetazepam has been included in studies using ultra-high performance liquid chromatography coupled with high-resolution time-of-flight mass spectrometry. This methodology is pivotal for the precise analysis of designer benzodiazepines and their pharmacokinetic properties, enhancing research in sedative biochemical studies and psychoactive drug research (Tomková et al., 2017).


• Forensic and Clinical Toxicology: Development and validation of gas chromatography-mass spectrometry methods for benzodiazepine drugs, including nimetazepam, highlight its application in both clinical and forensic toxicology. This approach facilitates the accurate detection and quantification of benzodiazepines in biological specimens, aiding in the management of conditions such as sleep disorders and anxiety (Papoutsis et al., 2010).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup