推薦產品
化驗
>99% (TLC)
形狀
ethanol solution
包裝
pkg of 1 × 1 mL (900128E-100UG)
pkg of 1 × 1 mL (900128E-500UG)
製造商／商標名
Avanti Research™ - A Croda Brand
濃度
100 μg/mL in ethanol (900128E-100UG)
500 μg/mL in ethanol (900128E-500UG)
運輸包裝
dry ice
儲存溫度
−70°C
InChI
1S/C20H32O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h4-5,8-11,14,17,19,21H,2-3,6-7,12-13,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,17-14+/t19-/m0/s1
InChI 密鑰
JSFATNQSLKRBCI-VAEKSGALSA-N
一般說明
15(S)-HETE is a product of the arachidonic acid pathway. It is synthesized by the human lungs and airway epithelial cells. 15(S)-HETE is a potent mucosecretagogue in human airways. It is a metabolite of 15-lipoxygenase. 15(S)-HETE is an endogenous ligand for peroxisome proliferator-activated receptor γ (PPARγ).
生化／生理作用
15(S)-HETE plays a role in various biological actions. It may play a role in pathogenesis and prevention of airway inflammatory disorders. 15(S)-HETE is involved in inhibiting cell proliferation and induces apoptosis in various human cancers.
包裝
2 mL Amber Glass Sealed Ampule (900128E-100UG and 900128E-500UG)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險聲明
危險分類
Eye Irrit. 2 - Flam. Liq. 2
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
55.4 °F
閃點（°C）
13 °C
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
15 (S)-HETE modulates LTB4 production and neutrophil chemotaxis in chronic bronchitis
Profita M, et al.
American Journal of Physiology. Cell Physiology, 279(4), C1249-C1258 (2000)
Huiling Yuan et al.
Thorax, 65(4), 321-326 (2010-04-15)
15-S-Hydroxyeicosatetraenoic acid (15(S)-HETE) and 13-S-hydroxyoctadecadienoic acid (13(S)-HODE), both of which are metabolites of 15-lipoxygenases (15-LOXs), are endogenous ligands for peroxisome proliferator-activated receptor gamma (PPARgamma). The activation of PPARgamma inhibits cell growth and induces apoptosis in some cancers. The role of
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