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125571

Sigma-Aldrich

5-氯-2-巯基苯并噻唑

technical grade, ≥90%

同義詞:

2-巯基-5-氯苯并噻唑, CMBT

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About This Item

經驗公式(希爾表示法):
C7H4ClNS2
CAS號碼:
分子量::
201.70
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

等級

technical grade

化驗

≥90%

mp

198-200 °C (lit.)

SMILES 字串

Sc1nc2cc(Cl)ccc2s1

InChI

1S/C7H4ClNS2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10)

InChI 密鑰

NKYDKCVZNMNZCM-UHFFFAOYSA-N

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相關類別

一般說明

5-Chloro-2-mercaptobenzothiazole(CMBZT) reacts with iodine in a molar ratio of 1:1 to form charge-transfer complex (CMBZT)I2.

應用

5-Chloro-2-mercaptobenzothiazole (CMBZT) has been used in the analysis of lipopolysaccharide by negative-ion matrix-assisted laser desorption ionization-time of flight mass spectrometry. It has been used in the synthesis of the new mixed ligand silver(I) chloride complex with the heterocyclic thioamide CMBZT and tri(p-tolyl)phosphine. Found to be more sensitive than DHB for analysis of high mannose N-linked glycans. Used in analysis of peptidoglycan muropeptides.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Chen Chen et al.
Biotechnology for biofuels, 11, 155-155 (2018-07-12)
Polysaccharide monooxygenases (PMOs) of the auxiliary activity 9 (AA9) family have been reported to oxidize C1, C4, and C6 positions in cellulose. However, currently no direct evidence exists that PMOs oxidize C6 positions in cellulose, and molecular mechanism of C1, C4
Adeline M Hajjar et al.
Infection and immunity, 74(12), 6730-6738 (2006-09-20)
Francisella tularensis is an intracellular gram-negative bacterium that is highly infectious and potentially lethal. Several subspecies exist of varying pathogenicity. Infection by only a few organisms is sufficient to cause disease depending on the model system. Lipopolysaccharide (LPS) of gram-negative
Synthesis and Characterization of (PTU) I2 (PTU= 6-n-propyl-2-thiouracil) and (CMBZT) I2 (CMBZT= 5-chloro-2-mercaptobenzothiazole) and Possible Implications for the Mechanism of Action of Anti-Thyroid Drugs.
Antoniadis CD, et al.
European Journal of Inorganic Chemistry, 2003(8), 1635-1640 (2003)
L Kyros et al.
Bioinorganic chemistry and applications, 386860-386860 (2010-04-10)
The synthesis and characterization of the silver(I) chloride complex of formula {[AgCI(CMBZT)(TPTP)(2)] . (MeOH)} (1) (CMBZT = 5-chloro-2-mercaptobenzothiazole, TPTP = tris(p-tolyl)phosphine) is described. Also the structure of the hydrate derivative {[AgCI(TPTP)(3)] . (0.5 . H(2)O)} (2) of the corresponding known
Ariadna Fernández-Calvet et al.
Scientific reports, 8(1), 6872-6872 (2018-05-04)
Airway infection by nontypeable Haemophilus influenzae (NTHi) associates to chronic obstructive pulmonary disease (COPD) exacerbation and asthma neutrophilic airway inflammation. Lipids are key inflammatory mediators in these disease conditions and consequently, NTHi may encounter free fatty acids during airway persistence.

文章

Glycosylation is known to have profound influence on various physiochemical, cellular and biological functions of proteins. Alterations in this modification are known to affect the immune system and have been associated with various pathological states such as cancer, rheumatoid arthritis, and inflammatory diseases.

Mass Spectrometry of Glycans, method comparison and products

Mass Spectrometry of Glycans, method comparison and products

條款

Mass Spectrometry of Glycans

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