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Merck

XPC

xeroderma pigmentosum, complementation group C

同義詞:
RAD4, XP3, XPCC
物種:
UniProtKB ID:
基因 ID:
  • Human(7508) Summary: This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(22591) xeroderma pigmentosum, complementation group C
  • Rat(312560) xeroderma pigmentosum, complementation group C
  • Zebrafish(541386) xeroderma pigmentosum, complementation group C
  • dog(476521) xeroderma pigmentosum, complementation group C
  • chicken(416039) xeroderma pigmentosum, complementation group C
  • domestic cat(101080440) xeroderma pigmentosum, complementation group C
  • Horse(100050424) xeroderma pigmentosum, complementation group C
  • naked mole-rat(101707002) xeroderma pigmentosum, complementation group C
  • Domestic Rabbit(100346279) xeroderma pigmentosum, complementation group C
  • domestic guinea pig(100719007) xeroderma pigmentosum, complementation group C
  • cow(524274) xeroderma pigmentosum, complementation group C
  • sheep(101109650) xeroderma pigmentosum, complementation group C

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Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-XPC antibody produced in mouse, ,
物種活性
human, mouse
應用
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
Anti-XPC (C-terminal) 兔抗, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
immunofluorescence
western blot
Anti-XPC antibody produced in rabbit, ,
物種活性
human
應用
immunocytochemistry
immunofluorescence

immunoprecipitation (IP)

western blot

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human XPC,
物種
human