跳轉至內容
Merck

VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

同義詞:
NR1I1
物種:
Human VDR (7421), Mouse Vdr (22337), Rat Vdr (24873), chicken VDR (395988), dog VDR (486588), Horse VDR (100034072), domestic cat VDR (100316614), cow VDR (533656), sheep VDR (101107273), sheep VDR (100294603) ...更多
UniProtKB ID:
P11473, B2R5Q1, G3V1V9, Q5PSV3
基因 ID:
  • Human(7421) Summary: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]
  • Mouse(22337) vitamin D receptor
  • Rat(24873) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • chicken(395988) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • dog(486588) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • Horse(100034072) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • domestic cat(100316614) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • cow(533656) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • sheep(101107273) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • sheep(100294603) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • naked mole-rat(101710294) vitamin D (1,25- dihydroxyvitamin D3) receptor
  • domestic guinea pig(100734655) vitamin D (1,25- dihydroxyvitamin D3) receptor

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

產品編號
描述
物種
C9756
胆钙化醇, ≥98% (HPLC),
物種
human
47763
胆钙化固醇（维生素 D3）, analytical standard,
物種
human
1131009
胆钙化醇, United States Pharmacopeia (USP) Reference Standard,
物種
human
95220
麦角钙化醇, ≥98.0% (sum of enantiomers, HPLC),
物種
human
V-025
维生素D3标准液 CRM 溶液, 1 mg/mL in ethanol, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human

Small Molecule - Antagonist

產品編號
描述
物種
D1530
1α,25-二羟基维生素D3, ≥99% (HPLC),
物種
human
17936
1α,25-二羟基维生素D3, ≥97.0% (HPLC),
物種
human

Antibodies

產品編號
描述
物種活性
應用
SAB4503071
Anti-Vitamin D Receptor antibody produced in rabbit, affinity isolated antibody,
物種活性
human
應用
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB1406580
Anti-VDR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
immunofluorescence
western blot
WH0007421M2
Monoclonal Anti-VDR antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunohistochemistry
SAB4504326
Anti-phospho-Vitamin D Receptor (pSer208) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
western blot
MABN1601
Anti-Vitamin D3 Receptor Antibody, clone 6F3.1, clone 6F3.1, from mouse,
物種活性
human
應用
western blot

esiRNA

產品編號
描述
物種
EHU010441
MISSION® esiRNA, targeting human VDR,
物種
human