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Merck

TNNC1

troponin C type 1 (slow)

同義詞:
CMD1Z, CMH13, TN-C, TNC, TNNC
物種:
UniProtKB ID:
基因 ID:
  • Human(7134) Summary: Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
  • Mouse(21924) troponin C, cardiac/slow skeletal
  • Rat(290561) troponin C type 1 (slow)
  • chicken(396032) troponin C type 1 (slow)
  • domestic cat(101082986) troponin C type 1 (slow)
  • dog(476595) troponin C type 1 (slow)
  • cow(509486) troponin C type 1 (slow)
  • sheep(101111132) troponin C type 1 (slow)
  • Goat(100860954) troponin C type 1 (slow)
  • domestic guinea pig(100730526) troponin C type 1 (slow)
  • naked mole-rat(101702386) troponin C type 1 (slow)

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Small Molecule - Allosteric Modulator

產品編號
描述
物種
Levosimendan, ≥98% (HPLC),
物種
human

Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-TNNC1 antibody produced in mouse, clone 1F8-A9, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunohistochemistry

western blot