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Merck

STAT5A

signal transducer and activator of transcription 5A

同義詞:
MGF, STAT5
物種:
UniProtKB ID:
基因 ID:
  • Human(6776) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
  • Mouse(20850) signal transducer and activator of transcription 5A
  • Rat(24918) signal transducer and activator of transcription 5A
  • dog(490968) signal transducer and activator of transcription 5A
  • Horse(100052904) signal transducer and activator of transcription 5A
  • domestic cat(101090913) signal transducer and activator of transcription 5A
  • cow(282375) signal transducer and activator of transcription 5A
  • sheep(443419) signal transducer and activator of transcription 5A
  • naked mole-rat(101723770) signal transducer and activator of transcription 5A
  • domestic guinea pig(100716811) signal transducer and activator of transcription 5A

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ELISA

產品編號
描述
物種
检测培养细胞系中磷酸化STAT5 (pTyr694)的基于细胞的ELISA试剂盒, 96 assays,
物種
human

Antibodies

產品編號
描述
物種活性
應用
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone 8-5-2, clone 8-5-2, Upstate®, from mouse,
物種活性
bovine, human, mouse, rat, sheep
應用
western blot
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone 94-10C-9-10C-2, rabbit monoclonal, clone 94-10C-9-10C-2, from rabbit,
物種活性
human, mouse, rat
應用
western blot
Anti-phospho-STAT5A/B (Ser726/Ser731) Antibody, serum, Upstate®,
物種活性
human, mouse, rat
應用
western blot
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone A11W, rabbit monoclonal, culture supernatant, clone A11W, from rabbit,
物種活性
bovine, chimpanzee, human, mouse, rat
應用
western blot
Anti-phospho-STAT5A (pTyr694) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot

Proteins

產品編號
描述
物種
STAT5,His 标记 人, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human STAT5A,
物種
human
MISSION® esiRNA, targeting mouse Stat5a,
物種
mouse