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Merck

SIRT2

sirtuin 2

同義詞:
SIR2, SIR2L, SIR2L2
物種:
UniProtKB ID:
基因 ID:
  • Human(22933) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]
  • Mouse(64383) sirtuin 2
  • Rat(361532) sirtuin 2
  • fruit fly(42414) CG5085 gene product from transcript CG5085-RA
  • chicken(548628) sirtuin 2
  • domestic cat(101099513) sirtuin 2
  • dog(612558) sirtuin 2
  • Zebrafish(322309) sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)
  • cow(504463) sirtuin 2
  • sheep(101113169) sirtuin 2
  • naked mole-rat(101715152) sirtuin 2
  • domestic guinea pig(100734519) sirtuin 2

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Small Molecule - Antagonist

Product Number
描述
物種
烟酰胺, BioReagent, suitable for cell culture, suitable for insect cell culture,
物種
human
烟酰胺, ≥99.5% (HPLC),
物種
human
烟酰胺, ≥98% (HPLC), powder,
物種
human
尼克酰胺(烟酰胺), analytical standard,
物種
human
烟酰胺, meets USP testing specifications,
物種
human

Antibodies

Product Number
描述
物種活性
應用
Monoclonal Anti-SIRT2 antibody produced in mouse, clone 4B11, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence

western blot
Anti-SIRT2 Antibody, from rabbit, purified by affinity chromatography,
物種活性
human, mouse
應用
immunoprecipitation (IP)
western blot
抗 Sirt2 兔抗, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse, rat
應用
immunofluorescence
immunoprecipitation (IP)

western blot

Proteins

Product Number
描述
物種
Sirtuin 2 human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
物種
human