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Merck

SETD2

SET domain containing 2

同義詞:
HBP231, HIF-1, HIP-1, HYPB, KMT3A, SET2, p231HBP
物種:
UniProtKB ID:
基因 ID:
  • Human(29072) Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
  • Mouse(235626) SET domain containing 2
  • Rat(316013) SET domain containing 2
  • Zebrafish(794199) SET domain containing 2
  • Horse(100064888) SET domain containing 2
  • domestic cat(101085029) SET domain containing 2
  • dog(476643) SET domain containing 2
  • chicken(420404) SET domain containing 2
  • cow(539860) SET domain containing 2
  • naked mole-rat(101719404) SET domain containing 2
  • domestic guinea pig(100719166) SET domain containing 2

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Antibodies

產品編號
描述
物種活性
應用
抗 SETD2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
immunofluorescence
immunohistochemistry
Anti-SETD2 antibody produced in rabbit, IgG fraction of antiserum,
物種活性
human
應用
immunohistochemistry
western blot
Anti-SETD2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
canine, human, mouse, pig
應用
ELISA
western blot

Proteins

產品編號
描述
物種
SETD2 active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
物種
human

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting mouse Setd2,
物種
mouse