SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
PI12, neuroserpin
Human SERPINI1 (5274), Mouse Serpini1 (20713), Rat Serpini1 (116459), Zebrafish serpini1 (557627), dog SERPINI1 (478684), domestic cat SERPINI1 (101090383), Horse SERPINI1 (100057410), chicken SERPINI1 (425002), Domestic Rabbit SERPINI1 (100341797), naked mole-rat Serpini1 (101716288) ...更多
- Human(5274) Summary: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Mouse(20713) serine (or cysteine) peptidase inhibitor, clade I, member 1
- Rat(116459) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- Zebrafish(557627) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- dog(478684) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- domestic cat(101090383) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- Horse(100057410) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- chicken(425002) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- Domestic Rabbit(100341797) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- naked mole-rat(101716288) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- domestic guinea pig(100733658) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- cow(509976) serpin peptidase inhibitor, clade I (neuroserpin), member 1
- sheep(101122566) serpin peptidase inhibitor, clade I (neuroserpin), member 1
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Proteins
Neuroserpin human, recombinant, expressed in E. coli, ≥96% (SDS-PAGE), ≥96% (HPLC), suitable for cell culture,
human