跳轉至內容
Merck

RRM2B

ribonucleotide reductase M2 B (TP53 inducible)

同義詞:
MTDPS8A, MTDPS8B, P53R2
物種:
UniProtKB ID:
基因 ID:
  • Human(50484) Summary: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
  • Mouse(382985) ribonucleotide reductase M2 B (TP53 inducible)
  • Rat(299976) ribonucleotide reductase M2 B (TP53 inducible)
  • cow(528960) ribonucleotide reductase M2 B (TP53 inducible)
  • sheep(101123639) ribonucleotide reductase M2 B (TP53 inducible)
  • naked mole-rat(101718446) ribonucleotide reductase M2 B (TP53 inducible)
  • domestic guinea pig(100715485) ribonucleotide reductase M2 B (TP53 inducible)
  • Zebrafish(368909) ribonucleotide reductase M2 b
  • chicken(420253) ribonucleotide reductase M2 B (TP53 inducible)
  • Horse(100062030) ribonucleotide reductase M2 B (TP53 inducible)
  • domestic cat(101099777) ribonucleotide reductase M2 B (TP53 inducible)
  • dog(481988) ribonucleotide reductase M2 B (TP53 inducible)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Inhibitor

產品編號
描述
物種
羟基脲, United States Pharmacopeia (USP) Reference Standard,
物種
human
羟基脲, European Pharmacopoeia (EP) Reference Standard,
物種
human
羟基脲, 98%, powder,
物種
human
吉西他滨, ≥98% (HPLC),
物種
human
吉西他滨, United States Pharmacopeia (USP) Reference Standard,
物種
human