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Merck

RHOC

ras homolog family member C

同義詞:
ARH9, ARHC, H9, RHOH9
物種:
UniProtKB ID:
基因 ID:
  • Human(389) Summary: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(11853) ras homolog gene family, member C
  • Rat(295342) ras homolog family member C
  • cow(513152) ras homolog gene family, member C
  • sheep(101118144) ras homolog family member C
  • naked mole-rat(101706654) ras homolog family member C
  • domestic guinea pig(100715557) ras homolog family member C
  • chicken(395869) ras homolog gene family, member C
  • domestic cat(101098319) ras homolog family member C
  • dog(483218) ras homolog family member C

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