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Merck

RBPJ

recombination signal binding protein for immunoglobulin kappa J region

同義詞:
AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
物種:
UniProtKB ID:
基因 ID:
  • Human(3516) Summary: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2011]
  • Mouse(19664) recombination signal binding protein for immunoglobulin kappa J region
  • Rat(679028) recombination signal binding protein for immunoglobulin kappa J region
  • chicken(422802) recombination signal binding protein for immunoglobulin kappa J region
  • Horse(100055547) recombination signal binding protein for immunoglobulin kappa J region
  • domestic cat(101100207) recombination signal binding protein for immunoglobulin kappa J region
  • dog(479122) recombination signal binding protein for immunoglobulin kappa J region
  • domestic guinea pig(100716535) recombination signal binding protein for immunoglobulin kappa J region
  • naked mole-rat(101726624) recombination signal binding protein for immunoglobulin kappa J region
  • cow(767928) recombination signal binding protein for immunoglobulin kappa J region
  • sheep(101107196) recombination signal binding protein for immunoglobulin kappa J region

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Antibodies

產品編號
描述
物種活性
應用
Anti-RBP-Jk, clone 1F1 Antibody, clone 1F1, from rat,
物種活性
drosophila, human
應用
ChIP
electrophoretic mobility shift assay

immunoprecipitation (IP)
Anti-RBPJ antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, rabbit, rat
應用
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-RBP-Jk Antibody, Chemicon®, from rabbit,
物種活性
human, mouse
應用
ChIP
immunohistochemistry

western blot

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting mouse Rbpj,
物種
mouse