RASA4
RAS p21 protein activator 4
同義詞:
CAPRI, GAPL
物種:
Human RASA4 (10156), Mouse Rasa4 (54153), Rat Rasa4 (288589), Zebrafish rasa4 (567599), Horse RASA4 (100060748), domestic cat RASA4 (101091420), dog RASA4 (489819), chicken RASA4 (417513), domestic guinea pig Rasa4 (100732664), naked mole-rat Rasa4 (101720607) ...更多
UniProtKB ID:
基因 ID:
- Human(10156) Summary: This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(54153) RAS p21 protein activator 4
- Rat(288589) RAS p21 protein activator 4
- Zebrafish(567599) RAS p21 protein activator 4
- Horse(100060748) RAS p21 protein activator 4
- domestic cat(101091420) RAS p21 protein activator 4
- dog(489819) RAS p21 protein activator 4
- chicken(417513) RAS p21 protein activator 4
- domestic guinea pig(100732664) RAS p21 protein activator 4
- naked mole-rat(101720607) RAS p21 protein activator 4
- cow(521224) RAS p21 protein activator 4
- sheep(101117299) RAS p21 protein activator 4
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