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Merck

PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

同義詞:
COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS
物種:
UniProtKB ID:
基因 ID:
  • Human(5742) Summary: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
  • Mouse(19224) prostaglandin-endoperoxide synthase 1
  • Rat(24693) prostaglandin-endoperoxide synthase 1
  • Zebrafish(246226) prostaglandin-endoperoxide synthase 1
  • dog(403544) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(100034087) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(101092557) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • chicken(427752) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100714030) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101698854) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • cow(282022) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443551) prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

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Antibodies

產品編號
描述
物種活性
應用
Anti-COX1 antibody produced in rabbit, affinity isolated antibody,
物種活性
human
應用
ELISA
immunohistochemistry

western blot
Anti-PTGS1 (AB1) antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, guinea pig, horse, human, mouse, rat, sheep
應用
immunohistochemistry
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
氟尼酸, ,
物種
human
安替比林, analytical standard,
物種
human
安替比林, United States Pharmacopeia (USP) Reference Standard,
物種
human
非那宗, European Pharmacopoeia (EP) Reference Standard,
物種
human
双氯芬酸 钠盐, ,
物種
human