PRKCZ
protein kinase C, zeta
同義詞:
PKC-ZETA, PKC2
物種:
Human PRKCZ (5590), Mouse Prkcz (18762), Rat Prkcz (25522), Domestic Rabbit PRKCZ (100009538), naked mole-rat Prkcz (101699303), domestic guinea pig Prkcz (100734946), cow PRKCZ (286877), sheep PRKCZ (101122295), Zebrafish prkcz (555737), chicken PRKCZ (419399) ...更多
UniProtKB ID:
基因 ID:
- Human(5590) Summary: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(18762) protein kinase C, zeta
- Rat(25522) protein kinase C, zeta
- Domestic Rabbit(100009538) protein kinase C, zeta
- naked mole-rat(101699303) protein kinase C, zeta
- domestic guinea pig(100734946) protein kinase C, zeta
- cow(286877) protein kinase C, zeta
- sheep(101122295) protein kinase C, zeta
- Zebrafish(555737) protein kinase C, zeta
- chicken(419399) protein kinase C, zeta
- domestic cat(101087851) protein kinase C, zeta
- dog(479577) protein kinase C, zeta
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Antibodies
Product Number
描述
物種活性
應用
Anti-PKC ζ antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-phospho-PKC ζ (pThr410) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-PKCζ Antibody, clone 14B12.3, clone 4B12.3, from mouse,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot
western blot
单克隆抗 蛋白激酶 C (PKC) 小鼠抗, clone MC5, ascites fluid,
物種活性
bovine, human, mouse, rat
應用
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunoprecipitation (IP)
microarray
western blot
Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Product Number
描述
物種
PKCζ, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human