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Merck

PRKCD

protein kinase C, delta

同義詞:
MAY1, PKCD, nPKC-delta
物種:
UniProtKB ID:
基因 ID:
  • Human(5580) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(18753) protein kinase C, delta
  • Rat(170538) protein kinase C, delta
  • chicken(415905) protein kinase C, delta
  • dog(494005) protein kinase C, delta
  • domestic cat(101087716) protein kinase C, delta
  • cow(505708) protein kinase C, delta
  • sheep(100294651) protein kinase C, delta
  • sheep(101107639) protein kinase C, delta
  • naked mole-rat(101718422) protein kinase C, delta
  • Domestic Rabbit(100008966) protein kinase C, delta
  • domestic guinea pig(100726624) protein kinase C, delta

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Small Molecule - Agonist

產品編號
描述
物種
油酸, ≥99% (GC),
物種
human

Antibodies

產品編號
描述
物種活性
應用
Anti-phospho-PKCδ (Ser664) Antibody, Upstate®, from rabbit,
物種活性
human
應用
western blot
Anti-Protein Kinase Cδ antibody produced in rabbit, whole antiserum,
物種活性
rat
應用
dot blot
microarray

western blot
Anti-PKC δ antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot
Anti-phospho-PKCD (pTyr64) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
佛波醇 12,13-二丁酸酯, ≥98% (TLC), powder,
物種
mouse
H-7 dihydrochloride, ≥98% (HPLC),
物種
human
他莫昔芬 柠檬酸盐, ≥99%,
物種
human
油酸, ≥99% (GC),
物種
human
UCN-01, ≥97% (HPLC), powder,
物種
human

Proteins

產品編號
描述
物種
PKCδ Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 2-end, of human PKCδ. For use in Kinase Assays.,
物種
human
PKC-δ, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human
Protein Kinase Cδ isozyme human, >95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
物種
human