PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
AAKG, AAKG2, CMH6, H91620p, WPWS
Human PRKAG2 (51422), Mouse Prkag2 (108099), Rat Prkag2 (373545), cow PRKAG2 (504219), sheep PRKAG2 (101104483), domestic guinea pig Prkag2 (100715315), naked mole-rat Prkag2 (101699641), Zebrafish prkag2 (568316), chicken PRKAG2 (420435), dog PRKAG2 (475546) ...更多
- Human(51422) Summary: AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(108099) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- Rat(373545) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- cow(504219) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- sheep(101104483) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- domestic guinea pig(100715315) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- naked mole-rat(101699641) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- Zebrafish(568316) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- chicken(420435) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- dog(475546) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- Horse(100034098) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- domestic cat(101100119) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
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