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Merck

PRKAG2

protein kinase, AMP-activated, gamma 2 non-catalytic subunit

同義詞:
AAKG, AAKG2, CMH6, H91620p, WPWS
物種:
UniProtKB ID:
基因 ID:
  • Human(51422) Summary: AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(108099) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • Rat(373545) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • cow(504219) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • sheep(101104483) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • domestic guinea pig(100715315) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • naked mole-rat(101699641) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • Zebrafish(568316) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • chicken(420435) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • dog(475546) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • Horse(100034098) protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • domestic cat(101100119) protein kinase, AMP-activated, gamma 2 non-catalytic subunit

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