PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
同義詞:
AMPK, AMPK2, AMPKa2, PRKAA
物種:
Human PRKAA2 (5563), Mouse Prkaa2 (108079), Rat Prkaa2 (78975), cow PRKAA2 (538954), sheep PRKAA2 (100127210), domestic guinea pig Prkaa2 (100713170), naked mole-rat Prkaa2 (101698482), Zebrafish prkaa2 (572074), Horse PRKAA2 (100034159), domestic cat PRKAA2 (101096000) ...更多
UniProtKB ID:
基因 ID:
- Human(5563) Summary: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
- Mouse(108079) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Rat(78975) protein kinase, AMP-activated, alpha 2 catalytic subunit
- cow(538954) protein kinase, AMP-activated, alpha 2 catalytic subunit
- sheep(100127210) protein kinase, AMP-activated, alpha 2 catalytic subunit
- domestic guinea pig(100713170) protein kinase, AMP-activated, alpha 2 catalytic subunit
- naked mole-rat(101698482) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Zebrafish(572074) protein kinase, AMP-activated, alpha 2 catalytic subunit
- Horse(100034159) protein kinase, AMP-activated, alpha 2 catalytic subunit
- domestic cat(101096000) protein kinase, AMP-activated, alpha 2 catalytic subunit
- chicken(429110) protein kinase, AMP-activated, alpha 2 catalytic subunit
- dog(489571) protein kinase, AMP-activated, alpha 2 catalytic subunit
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Antibodies
產品編號
描述
物種活性
應用
抗AMPK alpha 1/2抗体，克隆34.2, clone 34.2, from mouse,
物種活性
drosophila, human, mouse, rat
應用
western blot
Monoclonal Anti-PRKAA2 antibody produced in mouse, clone 1G8, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
ANTI-AMPK ALPHA2(C-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
human, mouse
應用
western blot
抗-磷酸化-AMPK α (pThr172) 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
產品編號
描述
物種
AMPK (α2, β1, γ1) Protein, active, 10 µg, Active, recombinant, human AMPK (α2, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα2, full length untagged AMPKβ1 & full length untagged AMPKγ1. For use in Kinase Assays.,
物種
human
AMPK (α2/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human